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Topical steroids control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Corticosteroids are also thought to act by the induction of phospholipase A2 inhibitory proteins. Topical salicylic acid has keratolytic properties as well as bacteriostatic and fungicidal actions.
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